There is apparently a new way to remain within the safe, warm universe that is World of Warcraft:
Tweetcraft. This apparently enables you to:
* Send/receive Tweets in-game (Immediate sending reloads your UI)
* Queue Tweets to send when it's more convenient for you
* Upload in-game screenshots using TwitPic
* AutoTweet when you log in, enter an instance or get an achievement
It is also, "Extensible so that AddOn authors can register messages or events to AutoTweet".